Rabu, 16 April 2014

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Cancer Clinical Trials: Current and Controversial Issues in Design and Analysis provides statisticians with an understanding of the critical challenges currently encountered in oncology trials. Well-known statisticians from academic institutions, regulatory and government agencies (such as the U.S. FDA and National Cancer Institute), and the pharmaceutical industry share their extensive experiences in cancer clinical trials and present examples taken from actual trials.

The book covers topics that are often perplexing and sometimes controversial in cancer clinical trials. Most of the issues addressed are also important for clinical trials in other settings. After discussing general topics, the book focuses on aspects of early and late phase clinical trials. It also explores personalized medicine, including biomarker-based clinical trials, adaptive clinical trial designs, and dynamic treatment regimes.

  • Sales Rank: #1202311 in Books
  • Published on: 2016-07-18
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.50" h x 6.50" w x 1.00" l, .0 pounds
  • Binding: Hardcover
  • 474 pages

About the Author

Stephen L. George, Ph.D., is professor emeritus of biostatistics in the Department of Biostatistics and Bioinformatics at the Duke University School of Medicine. For more than 20 years, he was director of biostatistics in the Duke Comprehensive Cancer Center and director of the Statistical Center of the Cancer and Leukemia Group B (CALGB). He has been closely involved in the design, conduct, and analysis of cancer clinical trials and other research projects in cancer throughout his career. He has served on and chaired data monitoring committees for treatment and prevention trials in cancer and other diseases. Dr. George is a fellow of the American Statistical Association and the Society for Clinical Trials. He also served as treasurer and member of the executive committee of the International Biometric Society, president of the Society for Clinical Trials, and biostatistician for the Oncologic Drugs Advisory Committee of the U.S. FDA.

Xiaofei Wang, Ph.D., is an associate professor of biostatistics and bioinformatics at the Duke University School of Medicine, a member of Duke Cancer Institute (DCI), and the director of statistics for the Alliance Statistics and Data Center (Alliance SDC). He has been involved in the design and analysis of cancer clinical trials and translational studies and served on special emphasis panels for NIH and FDA grants. His methodology research focuses on the development of novel designs and methods for biomarker-integrated clinical studies and methods for analyzing patient data from multiple sources. He obtained his Ph.D. in biostatistics from the University of North Carolina at Chapel Hill.

Herbert Pang, Ph.D., is an assistant professor in the School of Public Health, Li Ka Shing Faculty of Medicine (LKSFM) at the University of Hong Kong. Dr. Pang also holds an adjunct faculty position in the Department of Biostatistics and Bioinformatics at Duke University. He has been involved in the design, monitoring, and analysis of cancer clinical trials, translational, and big data-omics research in cancer for CALGB, Alliance SDC, DCI, and LKSFM. He has served on the editorial board of the Journal of Clinical Oncology and has received several honors, including the U.S. Chinese Anti-Cancer Association-Asian Fund for Cancer Research Scholar Award. He obtained his Ph.D. in biostatistics from Yale University and B.A. in mathematics and computer science from the University of Oxford.

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Sabtu, 12 April 2014

PDF Ebook Eleanor of Aquitaine: A Biography, by Marion Meade

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Eleanor of Aquitaine: A Biography, by Marion Meade

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Eleanor of Aquitaine: A Biography, by Marion Meade

About the Author

Marion Meade is the author of Dorothy Parker: What Fresh Hell Is This? and Bobbed Hair and Bathtub Gin: Writers Running Wild in the Twenties. She has also written biographies of Woody Allen, Buster Keaton, Eleanor of Aquitaine, Victoria Woodhull, and Madame Blavatsky, as well as two novels about medieval France.

Read more

Product details

Paperback: 416 pages

Publisher: Penguin Books (November 1, 1991)

Language: English

ISBN-10: 0140153381

ISBN-13: 978-0140153385

Product Dimensions:

6.2 x 1 x 9.3 inches

Shipping Weight: 1.2 pounds (View shipping rates and policies)

Average Customer Review:

4.1 out of 5 stars

39 customer reviews

Amazon Best Sellers Rank:

#913,549 in Books (See Top 100 in Books)

Although I have been acquainted with a turbulent life of this amasing woman in fits and starts by reading different other historical books (fiction and non-fiction), by far this book surpasses them in richness of detailes and thorough approach. Account of Eleanor's life starts with her ancestors, follows her happy cloudless childhood, sudden marriage to King Louis of France, her relations in this ill-matched union, participation in crusade, divorce, dazzling marriage to Henry II Plantagenet, her genious of administration and support of chivalry culture, birth of numerous "eaglets" and accounts of their lives, describes the cooling down of matrimonial passion, exile, return to glory with the rule of Richard the Lion Heart and disentegration of vast Plantagenet domains at John Lackland's rule after Eleanor's death. It is not a dry account of facts, but engrossing multicolored mosaic of names, feelings, deeds, customs and reasons. In her times a woman could be noted either by being a saint or too scandalous: Eleanor was neither, but worth while being remembered after 800 years. Although I must add that one can feel at once that the author is a woman and that the book was written in the 70s, when feministic movement was in its height and we just started to re-discover anew the role of women in history. However, now, 20 years later, after reading this book, no one would disagree, that the author overpraised her heroine - Eleanor of Aquitaine well deserves remembrance and admiration.

I am a lover and reader of biographies and histories. This book is very well written and is easy to follow. My ancestry traces back to Eleanor and I learned much that I had not known before. Highly recommend!

as advertised. Sadly, bar scan sticker right in the middle of the front cover. Does not peel off completely. LAME

Nothing compare to Amy Kelly. Too densely written.

Name 5 important women born between 100 a.d. and 1900 a.d. Eleanor of Aquitaine has to be on your list, perhaps in the first or second postion.Born in the 12th century, she married Louis VII of France, divorced him and married Henry II King of England. She bore 10 children, 2 to Louis, and 8 to Henry. Among them Prince John and Richard the lion hearted of Robin Hood fame.It was a time of great change. The Church was changing. It no longer saw women soley as the spawn of Satan. The cult of the Virgin Mary was taking hold. The politics of monarchy were changing. King Louis VII ruled only a small portion of what is modern day France. King Henry II wasn't even English, but a French nobleman who benefited from the untimely death of William the Conqueror's heir, and Civil War in England. He could "seize the day".(Horace) The second crusade led by Louis, failed miserably; perhaps some of modern day Muslin/Christian conflict has roots here. It appears that Louis did not heed Horace's advice.And Eleanor, where was she? Well she joined Louis on the Crusade. In fact she was blamed for the outcome of the first disasterous battle. It seems that it is easier to blame the queen and her excessive luggage, than the head of the crusading army. Thousands began the Crusade, only hundreds returned. It is not hard to imagine how Eleanor and the others felt. But, she was stuck with Louis. Or was she? Louis needed a male heir, and Eleanor had not produced one. Divorce was not what Louis wanted, but he did need that male heir, and Eleanor was not getting any younger. And so, he freed Eleanor.Imagine Louis' surprise at her marrying Henry just 8 weeks later. By the way she forgot to ask his permission. Louis was not happy.But Henry was. He got Eleanor and Acquitaine, 5 sons of which 4 survived to manhood, 3 daughters who through marriage, could be used to achieve his political ambitions. Everything is going so well. Then what does he do? Well, Henry falls in love. Eleanor moves out, back to Aquitaine. And then? The male children of this estranged couple plot against their father, then seek asylum with Louis Capet, Eleanor's X. Of course, mother Eleanor is easy to blame.In modern terms we might refer to this family as disfunctional. However, that disfunction had a price, and a payoff. France and England warred on and off over the next 300 years. Eleanor's decendants sat on the thrones of England, France, Jerusalem, and the Holy Roman Empire. We remember her today. And unlike many of the middle ages chroniclers, we think that she was important and we admire her.It is difficult to write a biography from the distance of eight or nine centuries. There are few reliable, contemporay sources. It is most difficult to write one about the most powerful woman in Europe, since few thought that women were important enough to chronicle except in the blame game. Marion Meade has done such an admirable job. Her biography make Eleanor come alive. That this book, copywrited in 1977, remains in print is a testament to her impecable research and excellent writing.I highly recommend this book.

I am almost finished reading this biography, and I have truly enjoyed it. Unlike other authors who actually write historical biographies versus historical fiction, the author, Marion Meade, actually makes Eleanor come to life, using what little researched facts available to her. Most other biographical authors of medieval women, because so little is documented about even famous women of those days, make the person seem so flat and impersonal. Ms. Meade actually brings Eleanor to life without adding fictional components. I will read more from this author in the future.

great history

A very well written account of Eleanor of Aquitaine's life, her accomplishments and legacy. I've enjoyed reading it.

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Jumat, 04 April 2014

Free Ebook Sheets of Sound for GuitarBy Jack A. Zucker

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Develop Extreme Chops for guitar. Applicable for all types of music from Shred to Classical to Jazz to Bluegrass to Chickin' Pickin'. This method is endorsed and utilized by some of the best guitarists in the world. There is NO better method for developing chops and efficiency on the instrument. -Tab and standard notation -Amazing Chops (works for Fusion, Metal, Jazz, etc) -Amazing blues scale applications -Sweep Picking to die for -Pick & Finger rolls -Incredible Arpeggios -Pentatonic Madness -4th and 5th chords and arpeggios -Odd Meter Phrasing -The most comprehensive Chord Sub methodology -Diminished lines like you've never seen before -Endorsed and used some of the best guitarists in the world

  • Amazon Sales Rank: #2117591 in Books
  • Brand: Brand: Jack A. Zucker
  • Published on: 2005-07-20
  • Original language: English
  • Number of items: 1
  • Binding: Spiral-bound
  • 296 pages
Features
  • Used Book in Good Condition

Review I love Jack's new book. As a professor at Berklee, I am always looking for new approach. -- Tomo FujitaI wholeheartedly recommend Jack Zucker's Sheets of Sound to any serious student of Jazz Guitar. -- Dr. Joseph JewellI'm starting to get into your book and I'm finding it facinating, fresh and VERY musical. -- Jamie Glaser (Chick Corea)Sheets of Sound is a unique and valuable resource that every guitarist should own. -- Jimmy BrunoSheets of Sound is a wonderful, book that would be a welcome addition to any guitarist's library. -- Rodney JonesSheets of Sound represents, to me, the most comprehensive treatise that I have ever encountered -- Frank Silk Smith (BB King)

About the Author

  • Performed and recorded with the Army Jazz Ambassadors
  • Studio Music/Guitar Major at the University of Miami
  • Played, performed and studied jazz guitar for over 30 years
  • Taught at Universities and privately for over 20 years.
  • Lectured on improvisation at jazz festivals
  • Studied with Bill Biesecker, Dennis Sandole, Pat Martino, Howard Roberts, Herb Ellis,

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    Stan Samole, Larry Wooldridge

  • Performed live broadcasts for the Today Show, numerous other television

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    Paul Bollenback, Dr. Glenn Cashman, Marc Copeland, Danny Gatton, Ellory

    Eskelin, Shannon Ford, Kathy Lee Gifford, Drew Gress, Jamey Haddad, Paul

    Horn, Bruce Hornsby, Randy Johnston, Greg Karukas, T. Lavitz, Mike Lee, Hank

    Levy, Joe Lovano, Rich Madison, Terry Plumeri, John Previti, Dianne Reeves,

    Howard Roberts, Jim Roberts, Dan Wall, Rick Whitehead, and many others.

  • Performed in pit-bands for many broadway shows in the DC area
  • Many local jazz performances in the DC and Cleveland area
  • Author of: Sheets of Sound for Guitar, a unique and exciting jazz guitar

    melodic/harmonic technique book. The book is used and endorsed by Henry Johnson, Jimmy Bruno, John Pisano, Paul Horn, T. Lavitz, Jamey Glaser, Ed Degenaro, and more.

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Jumat, 21 Maret 2014

Download Ebook Partial Differential Equations in Mechanics 2By A.P.S. Selvadurai

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  • Sales Rank: #3271542 in Books
  • Brand: Brand: Springer
  • Published on: 2000-11-27
  • Original language: English
  • Number of items: 1
  • Dimensions: 7.01" h x 1.56" w x 10.00" l, 3.48 pounds
  • Binding: Hardcover
  • 698 pages
Features
  • Used Book in Good Condition

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Selasa, 11 Maret 2014

Free Download The Bedford Glossary of Critical and Literary TermsBy Ross C. Murfin, Supryia M. Ray

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The Bedford Glossary of Critical and Literary TermsBy Ross C. Murfin, Supryia M. Ray

This volume engagingly and succinctly presents more than 700 traditional and contemporary critical and literary terms. Extensively cross-referenced, the alphabetically arranged entries are defined with unusual brevity and illustrated with hundreds of examples drawn from both canonical literature and contemporary popular culture. The glossary is expressly designed to meet the needs of students studying literature and criticism as it is taught today.

  • Sales Rank: #267353 in Books
  • Published on: 2003-01-21
  • Original language: English
  • Number of items: 1
  • Dimensions: .82" h x 6.26" w x 9.22" l,
  • Binding: Paperback
  • 539 pages

Amazon.com Review
The Bedford Glossary includes lengthy (and easy-to-follow) discussions of ideas including such biggies as cultural studies, deconstruction, feminist criticism, gender criticism, irony, Marxist criticism, the new historicism, poststructuralism, psychological criticism and psychoanalytic criticism, and reader-response criticism. More obscure terms--anagnorisis, epithalamium, Menippean satire, kenning--receive shorter but equally careful treatment. This is a clear and comprehensive reference for academics, intellectuals, and anyone else who wants to hold forth intelligently on subjects literary and critical. --Jane Steinberg

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Kamis, 20 Februari 2014

Download Watermelons How to Plant, Grow, and Harvest for the Backyard GardenerBy Lamar Sherrill

Download Watermelons How to Plant, Grow, and Harvest for the Backyard GardenerBy Lamar Sherrill

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Watermelons  How to Plant, Grow, and Harvest for the Backyard GardenerBy Lamar Sherrill

Watermelons How to Plant, Grow, and Harvest for the Backyard GardenerBy Lamar Sherrill


Watermelons  How to Plant, Grow, and Harvest for the Backyard GardenerBy Lamar Sherrill


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Watermelons  How to Plant, Grow, and Harvest for the Backyard GardenerBy Lamar Sherrill

Are you having trouble growing watermelons? Would you like to learn the secrets to growing watermelons.

This book will show you how to succeed in growing watermelons from your backyard garden.

What this book will do for you:

Introduce you to popular varieties of watermelons to grow in your garden with success.

When and where to plant for the best results

Recommended soil conditions, along with irrigation, and fertilizing with the proper fertilizers.

Types of pests and diseases to look out for and treatment for affected plants

Growing giant Watermelons in your own garden, want to win at the county fair for largest watermelon, the tips in this section will help you be on your way to a giant watermelon in your garden.

Also includes how to tell when a watermelon is ripe, everyone needs to know these 4 items.

  • Sales Rank: #766900 in eBooks
  • Published on: 2013-07-27
  • Released on: 2013-07-27
  • Format: Kindle eBook

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Rabu, 19 Februari 2014

Free PDF Chemical PrinciplesBy Peter Atkins, Loretta Jones

Free PDF Chemical PrinciplesBy Peter Atkins, Loretta Jones

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Chemical PrinciplesBy Peter Atkins, Loretta Jones

Chemical PrinciplesBy Peter Atkins, Loretta Jones


Chemical PrinciplesBy Peter Atkins, Loretta Jones


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Chemical PrinciplesBy Peter Atkins, Loretta Jones

Written for calculus-inclusive general chemistry courses, Chemical Principles helps students develop chemical insight by showing the connections between fundamental chemical ideas and their applications.  Unlike other texts, it begins with a detailed picture of the atom then builds toward chemistry's frontier, continually demonstrating how to solve problems, think about nature and matter, and visualize chemical concepts as working chemists do. 
 
Flexibility in level is crucial, and is largely established through clearly labeling (separating in boxes) the calculus coverage in the text: Instructors have the option of whether to incorporate calculus in the coverage of topics. 
 
The multimedia integration of Chemical Principles is more deeply established than any other text for this course.  Through the unique eBook, the comprehensive Chemistry Portal, Living Graph icons that connect the text to the Web, and a complete set of animations, students can take full advantage of the wealth of resources available to them to help them learn and gain a deeper understanding. 

  • Sales Rank: #406595 in Books
  • Published on: 2006-12-08
  • Original language: English
  • Number of items: 1
  • Dimensions: 11.00" h x 1.55" w x 8.84" l,
  • Binding: Hardcover
  • 1024 pages

About the Author
PETER ATKINS is a Professor of Chemistry at Oxford University, UK, a fellow of Lincoln College, and the author of more than fifty books for students and a general audience. His Physical Chemistry broke new ground by stressing understanding over memorization. Now in its Eighth edition, it remains the leading text in its field. LORETTA JONES is a Professor at the University of Northern Colorado, USA.

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